Transcriptional corepressors : mediators of eukaryotic gene repression

edited by Martin L. Privalsky

Corepressors are newly discovered assemblies of proteins that play essential roles in eukaryotic gene regulation. Recent discoveries about corepressors have provided new insights into the molecular basis of gene regulation, and have established surprising connections between the mechanisms of action of a wide variety of transcriptional regulators. The reviews in this volume critically discuss the nature, mechanisms of action, and physiological roles of corepressors in a diverse assortment of biological systems. Both basic and clinical investigators will be able to find relevant information. The comprehensive nature of the compilation, and the breadth of the reviews, are intended to provide the reader with an excellent introduction to the newly emergent and rapidly-growing field of corepressor research. A valuable and detailed reference guide.

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[目次]

  • Molecular Mechanisms of Corepressor Function.- Role of Histone Deacetylase Complexes in the Regulation of Chromatin Metabolism.- Corepressor Proteins and Control of Transcription in Yeast.- Corepressor Proteins in Drosophila Development.- Corepressors and Nuclear Hormone Receptor Function.- Regulation of SMRT and N-CoR Corepressor Function.- Corepressors and Retinoblastoma Protein Function.- Smad Transcriptional Corepressors in TGFss Family Signaling.- Role of Nuclear Receptor Corepressors in Leukemogenesis.

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この本の情報

書名 Transcriptional corepressors : mediators of eukaryotic gene repression
著作者等 Privalsky Martin L.
シリーズ名 Current topics in microbiology and immunology
出版元 Springer
刊行年月 c2001
ページ数 ix, 190 p.
大きさ 24 cm
ISBN 3540676112
NCID BA49726161
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言語 英語
出版国 ドイツ
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