Structure, proteins, and genetics

edited by K.L.Tyler and M.B.A.Oldstone

Reoviruses are one of the most important viral groups for understanding the molecular and genetic basis for viral pathogenesis. These two volumes cover virtually all aspects of reovirus biology. Volume I begins with a review of reovirus structure; further chapters deal with functions of the reovirus structural proteins, the assembly of the genome, and reovirus mutants. Volume II reviews general mechanisms of reovirus persistent infection and cytopathic effects, and then discusses reovirus-induced disease in specific organ systems including the heart, nervous and endocrine systems, liver and biliary system, and intestine. Together, these two volumes provide a current and comprehensive review of the mammalian reoviruses.

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  • Structure of mammalian orthoreovirus particles
  • enzymatic and control function of reovirus structural proteins
  • assembly of the reovirus genome
  • temperature-sensitive mutants of reovirus
  • suppression and reversion of mutant phenotype
  • reovirus cell attachment protein sigma1
  • signal transduction and antiproliferative function of mammalian receptor for type 3 reovirus
  • reovirus capsid protein sigma3 and my1
  • reovirus sigma3 protein - dsRNA binding and inhibition of RNA-activated protein kinase
  • reovirus M1 gene expression.

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書名 Structure, proteins, and genetics
著作者等 Oldstone, Michael B. A
Tyler, Kenneth L.
Oldstone M.B.A. (The Scripps Research Institute La Jolla California USA)
Tyler K.L. (University of Colorado Health Sciences Center Denver Colorado USA)
シリーズ名 Current topics in microbiology and immunology
出版元 Springer-Verlag
刊行年月 c1998
ページ数 xi, 223 p.
大きさ 25 cm
ISBN 3540639462
ISSN 0070217X
NCID BA35533895
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言語 英語
出版国 ドイツ