Pathogenicity islands and the evolution of pathogenic microbes  v. 1 ~ v. 2

edited by J. Hacker and J.B. Kaper

It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.

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It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well due to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.

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[目次]

  • Helicobacter pylori: Impact of gene transfer and the role of the cag pathogenicity islands for host adaptation and virulence.- The genus Neisseria: population structure, genome plasticity, and evolution of pathogenicity.- Genomic islands of Dichelobacter nodosus.- Phages and other mobile virulence elements in gram-positive pathogens.- Genome structure and evolution of the Bacillus cereus group.- Pathogenicity islands and virulence plasmids of bacterial plant pathogens.- Genome structure of pathogenic fungi.- Impact of integrons and transposons on the evolution of resistance and virulence.- Subject index.

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[目次]

  • Evolution of prokaryotic genomes.- Extraintestinal Escherichia coli as a model system for the study of pathogenicity islands.- Pathogenicity islands of intestinal E. coli.- Pathogenicity islands of Shigella.- Pathogenicity islands and host adaptation of Samonella serovars.- Plasmids and pathogenicity islands of Yersinia.- Genomic structure of LPS-specific loci.- Genomic structure of capsular determinants.- Genome plasticity of pathogenic and non-pathogenic enterobacteria.- Phylogenetic relationships and virulence evolution in the genus bordetella.- Pathogenicity islands and PAI-like structures in Pseudomonas species.- Subject index.

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この本の情報

書名 Pathogenicity islands and the evolution of pathogenic microbes
著作者等 Hacker, Jörg
Kaper, James B.
Hacker J.
シリーズ名 Current topics in microbiology and immunology
巻冊次 v. 1
v. 2
出版元 Springer
刊行年月 c2002
ページ数 2 v.
大きさ 24 cm
ISBN 3540426825
3540426817
NCID BA56633220
※クリックでCiNii Booksを表示
言語 英語
出版国 ドイツ
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