Structure-based Drug Discovery

edited by Harren Jhoti, Andrew R. Leach

This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions.

「Nielsen BookData」より

This book describes some of the most exciting developments for the discovery of new drugs, such as Fragment-based methods. It contains the latest developments in technologies that can be used to obtain the 3-D structures. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as well as other biophysical methods for studying protein/ligand interactions.

「Nielsen BookData」より

[目次]

  • Five Years of Increasing Structural Biology Throughput - A Retrospective Analysis.- Protein Production for Structural Genomics - Strategies for the Next Phase.- to Fragment Screening.- Fragment-Based NMR Screening in Lead Discovery.- Fragment-Based Screening by X-ray Crystallography.- Scaffold-Based Drug Discovery.- Biophysical Methods.- Illustration of Current Challenges in Molecular Docking.- Scoring Functions.

「Nielsen BookData」より

[目次]

  • Five Years of Increasing Structural Biology Throughput - A Retrospective Analysis.- Protein Production for Structural Genomics - Strategies for the Next Phase.- to Fragment Screening.- Fragment-Based NMR Screening in Lead Discovery.- Fragment-Based Screening by X-ray Crystallography.- Scaffold-Based Drug Discovery.- Biophysical Methods.- Illustration of Current Challenges in Molecular Docking.- Scoring Functions.

「Nielsen BookData」より

この本の情報

書名 Structure-based Drug Discovery
著作者等 Leach Andrew R.
Leach Andrew
Jhoti Harren
出版元 Springer
刊行年月 c2007
版表示 1st ed. Softcover of orig. ed. 2007
ページ数 xii, 249 p.
大きさ 25 cm
ISBN 1402044062
9789048171231
NCID BA81188378
※クリックでCiNii Booksを表示
言語 英語
出版国 オランダ
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