editors, R.A. Hill ... [et al.] ; principal contributors, A. Cooper, A.D. Roberts ; project editor, F.M. Macdonald
Steroids are a significant class of compound which occupy a central role in science today. Their wide range of biological activity has led to a large number of steroids finding clinical use as anticancer drugs, anti-inflammatory agents, contraceptives, diuretics and cardioactive agents. This reference is a compilation of chemical, structural and bibliographic data on the most interesting and important steroids known. It should prove useful to chemists working in this field. Bound in two volumes, this dictionary presents physical and chemical data, biological source and medicinal uses of over 15,000 steroids in 6,500 entries. Documentation is comprehensive for natural steroids (human, plant and animal), for example bile acids, sterols and steroidal alkaloids. Coverage is given of synthetic and semi-synthetic steroids including those of medicinal interest and those used as starting materials in synthesis. Every entry is given its systematic name and a trivial name where appropriate. Bibliographic data for each entry has been labelled to indicate content.
The current literature has been reviewed until September 1990 and while a small proportion of entries have come from the "Dictionary of Organic Compounds" these have been enlarged and updated; the majority are new with coverage of natural products. The indexes, which are bound in a separate volume for convenience, include Name, Molecular Formula, Type of Compound, CAS Registry Number and species. In the Type of Compound Index entries are arranged according to steroid ring structure or biological activity (for example pregnanes and andostranes) thus allowing steroids of a particular type to be easily found and compared. The Species index allows rapid access to the data using the botanical or zoological name. This book should be a useful reference source for steroid biochemists, natural product chemists, bile acid researchers, and medicinal and pharmaceutical chemists.