Nitroazoles : Synthesis, Structure and Applications

By (author) Larina, Lyudmila Ivanovna; By (author) Lopyrev, Valentin

The monograph gives an exhaustive and systematic description of the methods of synthesis, application, structure and properties of nitroazoles perspective medicines, universal bases in peptide nucleic acids, agrochemicals, and components of high-energy materials. All five-membered nitroderivatives of azoles - pyrazoles, imidazoles, triazoles, tetrazoles, oxazoles, isoxazoles, oxadiazoles, thiazoles, isothiazoles, thiadiazoles, and their benzanalogs - indazoles, benzimidazoles, benzoxazoles, benzisoxazoles, benzoxadiazoles, benzothiazoles, benzoisothiazoles, benzothiadiazoles, benzotriazoles are discussed in the book. Special attention is paid to the nitroimidazole derivatives many of which are well-known drugs and hypoxic cell radiosensitizers (azomycine, metronidazole, misonidazole, tinidazole, dimetridazole, ipronidazole, carnidazole and etc). The critical evaluation of a large body of the information on nitroazoles investigations by physicochemical methods (NMR, NQR, ESR, UV, IR- specrtoscopy, X-ray, mass-spectrometry, polarography, dipole moments and others methods) is presented here.

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  • Synthesis of Five-Membered Nitroazoles.- Synthesis of Nitrobenzazoles.- Structure and Physical-Chemical Properties of Nitroazoles.- Application of Nitroazoles.

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書名 Nitroazoles : Synthesis, Structure and Applications
著作者等 Lopyrev, Valentin
Larina, Lyudmila Ivanovna
書名別名 Synthesis, Structure and Applications
シリーズ名 Topics in Applied Chemistry
出版元 Springer-Verlag New York Inc.
刊行年月 2012.03.03
ページ数 459p
大きさ H235 x W155
ISBN 9781461424451
言語 英語
出版国 アメリカ合衆国