Higher Cognitive Function in Elderly Individuals with Previous Cataract Surgery: Cross-Sectional Association Independent of Visual Acuity in the HEIJO-KYO Cohort.

Cataract surgery improves visual acuity and drastically increases the capacity for light reception to the retina. Although previous studies suggested that both light exposure and visual acuity were associated with cognitive function, the relationships between cataract surgery, visual acuity, and cognitive function have not been evaluated in large populations. In this cross-sectional study, we measured cognitive function using the Mini-Mental State Examination and best-corrected visual acuity in pseudophakic (previous cataract surgery) and phakic (no previous cataract surgery) elderly individuals. Of 945 participants (mean age 71.7 years), 166 (17.6%) had pseudophakia and 317 (33.5%) had impaired cognitive function (score ≤26). The pseudophakic group showed significantly better visual acuity than the phakic group (p = 0.003) and lower age-adjusted odds ratio (ORs) for cognitive impairment (OR 0.66; p = 0.038). Consistently, in multivariate logistic regression models, after adjusting for confounding factors, including visual acuity and socioeconomic status, ORs for cognitive impairment were significantly lower in the pseudophakic group than in the phakic group (OR 0.64; 95% confidence interval 0.43-0.96; p = 0.031). This association remained significant in sensitivity analysis, excluding participants with low cognitive score ≤23 (n = 36). In conclusion, in a general elderly population, prevalence of cognitive impairment was significantly lower in pseudophakic individuals independently of visual acuity. The association was also independent of several major causes of cognitive impairment such as aging, gender, obesity, socioeconomic status, hypertension, diabetes, sleep disturbances, depressive symptoms, and physical inactivity.;博士(医学)・甲第666号・平成29年3月15日;© Mary Ann Liebert, Inc.;This is a non-final version of an article published in final form in "http://dx.doi.org/10.1089/rej.2015.1718";開始ページ : 239;終了ページ : 243;PubMed番号 : http://www.ncbi.nlm.nih.gov/pubmed/26414122

「国立国会図書館デジタルコレクション(雑誌)」より

この本の情報

書名 Higher Cognitive Function in Elderly Individuals with Previous Cataract Surgery: Cross-Sectional Association Independent of Visual Acuity in the HEIJO-KYO Cohort.
著作者等 Kurumatani, Norio
Morikawa, Masayuki
Nishi, Tomo
Obayashi, Kenji
Ogata, Nahoko
Saeki, Keigo
Tanaka, Kunihiko
Tone, Nobuhiro
Miyata, Kimie
書名別名 白内障手術既往のある高齢者は視力と独立して高い認知機能を維持する : 平城京コホート研究横断解析
出版元 Mary Ann Liebert, Inc.
刊行年月 c2004-
ページ数 v.
ISSN 15491684
NCID AA11965693
※クリックでCiNii Booksを表示
言語 英語
出版国 アメリカ合衆国
この本を: 
このエントリーをはてなブックマークに追加

Yahoo!ブックマークに登録
この記事をクリップ!
Clip to Evernote
このページを印刷

外部サイトで検索

この本と繋がる本を検索

ウィキペディアから連想