Can the use of intraoperative intact parathyroid hormone monitoring be abandoned in patients with hyperparathyroidism?

Background Ultrasound (US) and technetium-99m sestamibi scintigraphy (MIBI) are used to determine the localization of abnormal glands in cases of primary hyperparathyroidism (PHPT). Intraoperative intact parathyroid hormone (iPTH) monitoring is a reliable examination used to cure PHPT. The aim was to assess the necessity of intraoperative iPTH monitoring. Methods Sixty patients were examined using preoperative MIBI and US. iPTH was measured at 3 time points: (1) at the start of surgery; (2) 10 minutes after gland resection; and (3) more than 60 minutes after surgery. We defined a decreased iPTH level as an iPTH measured 10 minutes after resection that was less than 50% of the preoperative level. Results The iPTH of 55 patients with concordant lesions decreased to within the normal range more than 60 minutes after surgery. Conclusions It is not necessary to monitor intraoperative iPTH when single concordant lesions are preoperatively identified on both MIBI and US.;開始ページ : 574;終了ページ : 577;元資料の権利情報 : © 2013 Elsevier Inc.;元資料の権利情報 : NOTICE: this is the author's version of a work that was accepted for publication in The American Journal of Surgery. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in The American Journal of Surgery, 206, 4(2013)

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書名 Can the use of intraoperative intact parathyroid hormone monitoring be abandoned in patients with hyperparathyroidism?
著作者等 Elsevier Science Publishers
崎村 千香
書名別名 原発性副甲状腺機能亢進症における術中intact-PTHモニタリングの必要性の検討
出版元 Elsevier, Inc
ページ数 v.
大きさ 28 cm
ISSN 00029610
NCID AA11523108
AA00521348
AA00521326
※クリックでCiNii Booksを表示
言語 英語
出版国 アメリカ合衆国
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