Influence of the extent of aortic replacement on survival and quality of life in patients with aortic root replacement

Background: The influence of the extent of aortic replacement on the aortic root replacement is unclear. We investigated the clinical outcomes of the aortic root replacement in terms of the extent of aortic replacement and evaluated quality of life (QOL) after surgery. Methods: Thirty six patients were enrolled in this study. The mean age was 59.0 ± 13.1 years. The 36 patients were divided into three groups according the extent of aortic replacement: 21 patients with replacement of the ascending aorta (SB), 7 patients with hemi-arch replacement (HB), and 8 patients with total aortic arch replacement (TB). Postoperative health-related QOL was evaluated by SF-36 Version 2. Results: The hospital mortality in the 36 patients was 2.8%. The patient (TB) died from fungal infection of the prosthetic graft. Three late deaths (8.6%) were observed: cerebral hemorrhage in one (SB), pneumonia in one (SB), and unknown in one (HB). The 5-year survival was 94.1 ± 5.7% in the SB group, 100% in the HB and 87.5 ± 11.7% in the TB groups, respectively (p=0.84). One patient (4.8%) in the SB group had an aorta-related event 7 years after surgery. No patinets had aorta-related events in both the HB and the TB groups. There was no significant difference in postoperative health-related QOL among the three groups. Conclusions: Aortic root replacement at our hospital achieved excellent results. Neither long-term survival nor postoperative QOL differed significantly according to the extent of aortic root replacement. We plan to extend the present study by including a larger number of subjects.;開始ページ : 49;終了ページ : 56;元資料の権利情報 : © 2013 Nagasaki University School of Medicine

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書名 Influence of the extent of aortic replacement on survival and quality of life in patients with aortic root replacement
著作者等 長崎大学医学部
小野原 大介
書名別名 基部置換術における大動脈置換範囲の違いによる手術成績の比較・検討
出版元 長崎大学医学部
刊行年月 1939-
ページ数 v
ISSN 00016055
NCID AA00508430
AA12022006
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全国書誌番号
10012300
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言語 英語
出版国 日本
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