Psychiatric epidemiology : searching for the causes of mental disorders

Ezra Susser ... [et al.]

Searching for the causes of mental disorders is as exciting as it is complex. The relationship between pathophysiology and its overt manifestations is exceedingly intricate, and often the causes of a disorder are elusive at best. This book is an invaluable resource for anyone trying to track these causes, whether they be clinical researchers, public health practitioners, or psychiatric epidemiologists-in-training. Uniting theory and practice in very clear language, it makes a wonderful contribution to both epidemiologic and psychiatric research. Rather than attempting to review the descriptive epidemiology of mental disorders, this book gives a much more dynamic exposition of the thinking and techniques used to establish it. Starting out by tracing the brief history of psychiatric epidemiology, the book describes the study of risk factors as causes of mental disorders. Subsequent sections discuss approaches to investigation of biologic, genetic or social causes and the statistical analysis of study results. The book concludes by following some of the problems involved in the search for genetic causes of mental disorders, and more complex causal relationships.

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[目次]

  • PART I PSYCHIATRIC EPIDEMIOLOGY, THEN AND NOW
  • 1. The Burden of Mental Illness
  • 2. The Arc of Epidemiology
  • 3. Searching for the Causes of Mental Disorders
  • PART II RISK FACTORS AS CAUSES OF MENTAL DISORDERS
  • 4. What Is a Cause?
  • 5. Detecting Causes
  • 6. Study Designs
  • 7. Relationships among Causes
  • 8. Measures of Association
  • PART III COHORT DESIGNS IN PSYCHIATRIC EPIDEMIOLOGY
  • 9. Prototypical Cohort Study
  • 10. Diversity of Cohort Studies
  • 11. Causal Interference: A Thought Experiment
  • 12. Confounding: What It Is and What Can Be Done
  • 13. Unequal Attrition under Different Types of Follow-Up
  • 14. Differential Misclassification
  • PART IV CASE-CONTROL DESIGNS IN PSYCHIATRIC EPIDEMIOLOGY
  • 15. Logic of the Case-Control Design
  • 16. Applications of the Case-Control Study
  • 17. Choosing Controls
  • 18. Comparability and the Case-Control Study
  • PART V CASE-CONTROL DESIGNS IN BIOLOGIC PSYCHIATRY
  • 19. Biologic Studies in Psychiatry
  • 20. Choosing Cases in Biologic Psychiatry
  • 21. Choosing Controls in Biologic Psychiatry
  • PART VI ANALYZING THE DATA
  • 22. Gauging the Precision of Measures of Association
  • 23. Using Significance Tests in Establishing Associations
  • 24. Planning Studies: Estimating Power and Sample Size
  • 25. Adjustment for Covariates
  • 26. Event Time Analysis
  • 27. Assessing Heterogeneity of Effects
  • PART VII THE SEARCH FOR GENETIC CAUSES OF MENTAL DISORDERS
  • 28. Integrating Epidemiology with Genetics
  • 29. Genetic Association Studies
  • 30. Modern Family History Studies
  • 31. Twin Studies of Heritability
  • 32. Genetic Linkage Studies
  • 33. Designs for the Genomic Era
  • PART VIII COMPLEX CAUSAL RELATIONSHIPS
  • 34. Eco-Epidemiology
  • 35. Causal Explanation within a Risk Factor Framework
  • 36. Causal Explanation Outside the Black Box
  • 37. Dependent and Dynamic Processes
  • Appendix A. Our Approach to Epidemiologic Concepts and Methods
  • Appendix B. Application of Survival Analysis to Prenatal Determinants of Schizophrenia Example (PDSE) Data

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この本の情報

書名 Psychiatric epidemiology : searching for the causes of mental disorders
著作者等 Susser, Ezra S
Bromet Evelyn J.
Susser Ezra (Columbia University New York)
出版元 Oxford University Press
刊行年月 2006
ページ数 xxii, 516 p.
大きさ 26 cm
ISBN 9780195101812
NCID BA88084530
※クリックでCiNii Booksを表示
言語 英語
出版国 アメリカ合衆国
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