Studies on the structure of multi-domain protein in the eukaryotic signal transduction

[目次]

  • TABLE OF CONTENTS / p1
  • SUMMARY / p4
  • ABBREVIATIONS / p5
  • CHAPTER1 INTRODUCTION / p7
  • STRUCTURAL STUDIES ON MULTIDOMAIN PROTEIN / p8
  • BIOLOGICAL FUNCTION OF GRB2 IN EUKARYOTIC SIGNALING / p9
  • PURPOSE OF THIS STUDIES / p10
  • THE ARRANGEMENT OF CHAPTERS IN THIS THESIS / p11
  • TABLE AND FIGURE / p14
  • CHAPTER2 CHEMICAL SHIFTS ASSIGNMENT OF GRB2 COMPLEXED WITH LIGAND PEPTIDES / p18
  • ABSTRACT / p19
  • INTRODUCTION / p20
  • RESULTS AND DISCUSSION / p21
  • EXPERIMENTAL PROCEDURES / p26
  • TABLE AND FIGURE / p31
  • CHAPTER3 SOLUTION STRUCTURE OF GRB2 DELINEATED FROM NMR STUDIES / p51
  • ABSTRACT / p52
  • INTRODUCTION / p53
  • RESULTS AND DISCUSSION / p54
  • EXPERIMENTAL PROCEDURE / p60
  • TABLE AND FIGURE / p62
  • CHAPTER4 SMALL ANGLE X-RAY SCATTERING STUDY AND SOLUTION STRUCTURE MODEL / p73
  • ABSTRACT / p74
  • INTRODUCTION / p75
  • RESULTS AND DISCUSSION / p76
  • EXPERIMENTAL PROCEDURE / p80
  • TABLE AND FIGURE / p83
  • CHAPTER5 CONFORMATIONAL ADAPTATION WITH DOMAIN REARRANGEMENT OF GRB2 TO CONSOLIDATED LIGANDS / p94
  • ABSTRACT / p95
  • INTRODUCTION / p96
  • RESULTS AND DISCUSSION / p98
  • EXPERIMENTAL PROCEDURE / p102
  • TABLE AND FIGURE / p105
  • CHAPTER6 CONCLUDING REMARKS / p113
  • SUMMARY AND GENERAL DISCUSSION / p114
  • PERSPECTIVES ON GRB2 RESEARCH / p117
  • ACKNOWLEDGMENTS / p118
  • REFERENCE / p119

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この本の情報

書名 Studies on the structure of multi-domain protein in the eukaryotic signal transduction
著作者等 湯澤 聰
書名別名 真核生物のシグナル伝達に関わるマルチドメイン蛋白質の構造に関する研究
刊行年月 [2001]
言語 英語
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