Critical role of TIE-2 endothelial receptor tyrosine kinase in the development of hematopoietic and endothelial cells

[目次]

  • CONTENTS / p2
  • Preface / p4
  • Summary / p5
  • Publication list / p7
  • Acknowledgments / p8
  • Abbreviation / p10
  • Chapter one:General introduction / p12
  • 1.1.The hemangioblast:a common precursor for both hematopoietic and endothelial lineages / p12
  • 1.2.Development of the hematopoietic system / p15
  • 1.3.Vasculogenesis and angiogenesis / p20
  • Chapter two:Special introduction / p24
  • 2.1.Receptor tyrosine kinases and their ligands which are involved in development of both hematopoietic and endothelial lineages / p24
  • 2.2.Biological aspects of TIE-2 / p26
  • 2.3.Ligands of TIE-2:Angiopoietins / p28
  • 2.4.research purpose / p34
  • Chapter three:Methodology / p37
  • 3.1.Cell preparation and culture conditions / p37
  • 3.2.Immunohistochemistry / p37
  • 3.3.Flow cytometric analysis and cell sorting / p38
  • 3.4.Progenitor assay by methylcellulose culture / p38
  • 3.5.Adhesion of primary TIE-2⁺cells / p39
  • 3.6.Uptake of acetylated low-density lipoprotein labeled with Dil by endothelial cells / p39
  • 3.7.Spleen colony assay / p40
  • Chapter four:In vitro hematopoietic and endothelial cell development from TIE-2 expressing cells in AGM region--in embryo / p42
  • Results / p42
  • Discussion / p45
  • Chapter five:In vitro effects of Angiopoietins and VEGF on hematopoietic and endothelial cells--in bone marrow / p50
  • Results / p50
  • Discussion / p52
  • Epilogue / p55
  • List of figures / p57
  • List of tables / p58
  • References / p59
  • Legends of figures / p68

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この本の情報

書名 Critical role of TIE-2 endothelial receptor tyrosine kinase in the development of hematopoietic and endothelial cells
著作者等 黄 旭玲
書名別名 造血細胞と内皮細胞の発達におけるTIE-2内皮レセプターチロシンキナーゼの役割
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